Acetaminophen

Acetaminophen         In the late 1800s it was disc overed that papa-amino-phenol, could shave fever, neverthe little the drug was too cyanogenetic to use. A less(prenominal) hepatotoxic extract called phenacetin was later found to be serious as effective but also had fuss-relieving properties. In 1949, it was intimate that phenacetin was metabolized into an active but also less toxic drug, acetaminophen. Since then, acetaminophen has been sold under many over the tax return brand names, most popular organism Tylenol.         Acetaminophen serves unrivaled basic purpose, to relieve pain. It is the main portion in pain killers that relieve headaches. It also substitutes anaesthesia in circumcision surgery because anesthesia often can non be utilize on infants. Dr. Michael Weitzman and 2 new(prenominal) doctors performed an experiment on an infant to interrogatory the effectiveness of the drug. The results were not identical, but there w ere increases in nucleus rate respiratory rate and crying. But the drug did much good as a pain reliever afterwards the surgery than forrader the surgery.          Acetaminophen is ingested orally and is rapidly and tout ensemble absorbed into the gastrointestinal tract. It works in about champion hour. The liver detoxifies 90% of it by mixing it with sulfuric acid, and an dissimilar 3-5% is catabolized by enzyme reactions to the acid. The metabolites atomic number 18 excreted in the urine.

The loony toons of the drug should be used harmonise to the carton instructions. A 10 gram over point in adult s, cxl mg for kids, can cause imperishable! liver damage. as well as if you had just taken some other drugs , The acetaminophen may become more toxic since the drugs atomic number 18 catabolized in the liver. To protect yourself from injury, you should take 1 gram of vitamin C and Cysteine -a bodily antioxidant.          The kidneys can be permanently damaged if you unceasingly take the drug over a long underweight of... If you want to get a full essay, order it on our website: OrderCustomPaper.com

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